Shafa Orthopedic Journal

Published by: Kowsar

Evaluation of Delayed Effect of Intra-Articular Injection of Cefazolin, Gentamicin and Vancomycin on Articular Cartilage: an Experimental Study in Rabbits

Hamid Reza Yazdi 1 , * , Reza Jamei Moayedi 2 , Mohammad Ali Shokrgozar 3 , Mohammad Mehdi Dehghan 4 and Tahmineh Mokhtari 5
Authors Information
1 MD, Assistant Professor, Department of Orthopedic Surgery, Firoozgar Hospital, Iran University of Medical Science, Tehran, IR Iran
2 MD, Resident of Orthopedics, Department of Orthopedic Surgery, Shafa Orthopedic Hospital, Iran University of Medical Science, Tehran, IR Iran
3 PhD, National Cell Bank of Iran, Pasteur Institute of Iran, Tehran, IR Iran
4 DVM, Veterinary Surgeon, Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, IR Iran
5 PhD student of Anatomy, Department of Anatomy, School of Medicine, Tehran University of Medical Science, Tehran, IR Iran
Article information
  • Shafa Orthopedic Journal: August 30, 2014, 1 (3); e29
  • Published Online: August 1, 2014
  • Article Type: Research Article
  • Received: March 16, 2013
  • Revised: April 9, 2013
  • Accepted: June 12, 2013

To Cite: Yazdi H R, Jamei Moayedi R, Shokrgozar M A, Dehghan M M, Mokhtari T. et al. Evaluation of Delayed Effect of Intra-Articular Injection of Cefazolin, Gentamicin and Vancomycin on Articular Cartilage: an Experimental Study in Rabbits, Shafa Ortho J. 2014 ;1(3):e29.

Abstract
Copyright: Copyright © 0, Shafa Orthopedic Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
References
  • 1. Archer CW, Francis-West P. The chondrocyte. Int J Biochem Cell Biol. 2003; 35(4): 401-4[PubMed]
  • 2. Cheng SC, Jou IM, Chern TC, Wang PH, Chen WC. The effect of normal saline irrigation at different temperatures on the surface of articular cartilage: an experimental study in the rat. Arthroscopy. 2004; 20(1): 55-61[DOI][PubMed]
  • 3. Gradinger R, Trager J, Klauser RJ. Influence of various irrigation fluids on articular cartilage. Arthroscopy. 1995; 11(3): 263-9[PubMed]
  • 4. Mah ET, Lee WK, Southwood RT, Carbone A, Leppard PJ. Effects of irrigation fluid on human menisci: an experimental comparison of water, normal saline, and glycine. Arthroscopy. 1991; 7(1): 24-32[PubMed]
  • 5. Yang CY, Cheng SC, Shen CL. Effect of irrigation fluids on the articular cartilage: a scanning electron microscope study. Arthroscopy. 1993; 9(4): 425-30[PubMed]
  • 6. Akgun U, Kocaoglu B, Ergun S, Karahan M, Turkmen M. The effect of environmental pH change on bovine articular cartilage metabolism: implica-tions for the use of buffered solution during arthros-copy? . Knee Surg Sport Traumatol Arthrosc. 2013; : 1-6
  • 7. Chu CR, Coyle CH, Chu CT, Szczodry M, Seshadri V, Karpie JC. In vivo effects of single intra-articular injection of 0.5% bupivacaine on articular cartilage. J Bone Joint Surg Am. 2010; 92(3): 599-608[DOI][PubMed]
  • 8. Yang CY, Cheng SC, Shen CL. Effect of irrigation fluids on the articular cartilage: a scanning electron microscope study. Arthroscopy. 1993; 9(4): 425-30[PubMed]
  • 9. Anglen JO. Comparison of soap and antibiotic solutions for irrigation of lower-limb open fracture wounds. A prospective, randomized study. J Bone Joint Surg Am. 2005; 87(7): 1415-22[DOI][PubMed]
  • 10. Lescun TB, Adams SB, Wu CC, Bill RP, Van Sickle DC. Effects of continuous intra-articular infusion of gentamicin on synovial membrane and articular cartilage in the tarsocrural joint of horses. Am J Vet Res. 2002; 63(5): 683-7[PubMed]
  • 11. Haerdi-Landerer MC, Suter MM, Steiner A. Intra-articular administration of doxycycline in calves. Am J Vet Res. 2007; 68(12): 1324-31[DOI][PubMed]
  • 12. Jurvelin JS, Jurvelin JA, Kiviranta I, Klauser RJ. Effects of different irrigation liquids and times on articular cartilage: an experimental, biomechanical study. Arthroscopy. 1994; 10(6): 667-72[PubMed]
  • 13. McAlinden A, Haag J, Bau B, Gebhard PM, Aigner T. Quantification of mRNA expression levels in articular chondrocytes with PCR technologies. Methods Mol Med. 2004; 100: 79-100[DOI][PubMed]
  • 14. Edin ML, Miclau T, Lester GE, Lindsey RW, Dahners LE. Effect of cefazolin and vancomycin on osteoblasts in vitro. Clin Orthop Relat Res. 1996; (333): 245-51[PubMed]
  • 15. Rathbone CR, Cross JD, Brown KV, Murray CK, Wenke JC. Effect of various concentrations of antibiotics on osteogenic cell viability and activity. J Orthop Res. 2011; 29(7): 1070-4[DOI][PubMed]
  • 16. Antoci VJ, Adams CS, Hickok NJ, Shapiro IM, Parvizi J. Antibiotics for local delivery systems cause skeletal cell toxicity in vitro. Clin Orthop Relat Res. 2007; 462: 200-6[DOI][PubMed]
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