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Showing 13 results for KHATAMI

Seyyed Massoud KHATAMI,
Volume 12, Issue 2 (8-1998)

In addition to the liver, human hydatidosis has been reported in the lung, brain, abdominal viscera, muscles, and heart chambers. Infarction of the brain has also been documented. Arterial embolism of the lower extremities by hydatid cyst, however, is extremely rare. In the presented case, acute ischemia of the patient's left leg led to gangrene and amputation. Complete workup for localization of the primary focus of hydatid cyst was inconclusive however, the most probable explanation is spontaneous rupture of a left ventricular wall hydatid cyst which subsequently embolized to the aorta and lodged in the left femoral artery
Mr Esmaili Duki, Gr KHATAMI, M Najafi, A Khodadad,
Volume 13, Issue 1 (5-1999)

Celiac disease (CD) is defined as a permanent intolerance to gluten with clinical manifestations and abnormal small intestinal mucosa. A case series study was performed to obtain information about clinical manifestations, age of presentation and diagnosis of CD. For this purpose, hospital records of patients who were admitted to the gastrointestinal ward in the Children's Medical Center from 1986 to 1996 with suspected diagnosis of CD and discharged with such a diagnosis were reviewed. Thirty-five patients (17 male, 18 female) with diagnostic criteria for CD were selected and followed, The average age of onset was 3.07 years but mean age of diagnosis (the first small intestinal biopsy) was 7.7 years. The most common symptom was chronic diarrhea. The interval between initial symptoms and diagnosis was surprisingly long. During this period these subjects had multiple medical visits at different hospitals. With recognition of this treatable disorder and by available diagnostic procedures and obtaining small intestinal biopsy specimens, we can reduce the mentioned interval and diagnose this entity earlier in Iranian children.
Behzad Einollahi, Mohammadreza KHATAMI, Mahboob Lesanpezeshki, Pejman Bakhtiari, Violet Amirjalali, Ahmad Firouzan,
Volume 13, Issue 3 (11-1999)

A perplexing issue in diagnosing the cause of renal allograft dysfunction is differentiation between rejection----the most common cause--and many other possibilities that have detrimental effects on graft function. This study was designed to determine whether technetium - 99m sulfur colloid (TSC) accumulation could predict graft rejection. We prospectively studied 54 episodes of allograft dysfunction in 53 kidney transplant recipients who had undergone TSC scintiscanning and graft biopsy, within one week of evidence of allograft dysfunction. Visual analysis of TSC uptake was done by comparing allograft uptake with that of the fifth lumbar vertebra (L5) marrow. A 3+ result meant that allograft uptake was greater than L5 marrow uptake 2+, allograft uptake was the same as L5 marrow uptake 1+, less than and 0, no allograft uptake. Transplant accumulation of 􀁀2+ was considered consistent with rejection (p=0.01). Allotransplant biopsies were interpreted based on the Banff Working Classification and rejection was noted in 45 of 54 renal biopsies. 42 of 45 biopsy -proven rejection episodes had ≥2+ graft uptake. This nuclear medicine technique has a sensitivity of 93.3%, specificity of 44.4%, a positive predictive value of 89.3%, a negative value of 57.1 % and an efficiency of 83.3% in the diagnosis of renal allograft rejection.
Z Zamani, H Zolfagharian, H Towfighi, S KHATAMI, A Ansari,
Volume 13, Issue 4 (2-2000)

Snake venoms contain a rich variety of factors which affect blood coagulation. There have been few reports on the anticoagulant activity of the venom of different cobras, but no such observations have been made on the Iranian cobra, although a procoagulant factor has been described. In this study an anticoagulant factor has been purified from the venom of Naja naja oxiana using gel filtration followed by isopycnic ultracentrifugation with 30% KBr. The factor was a glycoprotein with a molecular weight of 45.36 kDa and increased plasma recalcification time by 224 sec which was 7.7 times greater than the activity of crude venom.
Farahnaz Fallahian, Mohammad Reza KHATAMI , Parviz Jabal Ameli, Abas Rahimi,
Volume 14, Issue 1 (5-2000)

Renal transplantation is considered one of the best long-term therapies for chronic renal failure, but unfortunately the incidence of malignancy significantly increases in renal transplant recipients. We analyzed nine cases of malignancy in 200 renal transplant recipients occurring in a 12-year follow-up in Imam hospital of Tehran University, Tehran, Iran. According to this study, the organ most commonly affected with malignancy in our series was the skin and the mean time of neoplasm occurrence after kidney transplantation was 2.9 years.
Farahnaz Fallahian, Mohammad Reza KHATAMI, Parviz Jabal Ameli,
Volume 14, Issue 2 (8-2000)

Neurologic and psychologic complications are usually related to drug toxicity, infections or symptoms induced by deterioration of renal allograft function. Metabolic encephalopathy, hypertensive encephalopathy, cerebrovascular events, and new-onset seizures have all been reported in organ-transplant recipients. Infections can be caused by listeria, cryptococcus, nocardia, aspergillus and mucor. Toxoplasma, coccidia, cytomegalovirus (CMV) and herpes infections are also reported. Cerebral hemorrhage can occur secondary to septic emboli or intracerebral aneurysms. The aim of this study is to present the results of a review on 200 renal transplant recipients concerning neuropsychologic complications during a 12-year period in the Imam Khomeini Hospital affiliated to Tehran University of Medical Sciences. According to this study, neuropsychologic disorders occurred in 3 a (15%) of the recipients and of these, peripheral neuropathy, depression and tremor were the most common and were detected in 8 (4%), 5 (2.5%), and 4 (2%) of the recipients, respectively.
S Ghazizadeh, M Lesan Pezeshki, B Einollahi, Mr KHATAMI,
Volume 15, Issue 1 (5-2001)

A retrospective study was conducted on 50 pregnancies in 41 kidney transplant recipients. 37 pregnancies were successful (74%), while in 13 cases the pregnancy was lost (7 abortions,S intra-uterine fetal deaths and one therapeutic termination). The pregnancy course was uneventful in 38 cases (76%) but in 12 there were complications, such as hypertension or slight rise in serum creatinine. Pregnancy was terminated in one case because of acute rejection, which then responded well to treatment and graft function returned to normal. Two cases of congenital anomaly were detected.
Mehri Najafi, Ahmad Khodadad, Gholam Reza KHATAMI,
Volume 18, Issue 4 (11-2005)

A 34 day-old girl infant was admitted for poor feeding and cholestasis. She had a bulging fontanelle, with no evidence of intracranial infection or hemorrhage. Investigations demonstrated that she had galactosemia. Computed tomographic scans demonstrated the presence of diffuse cerebral edema. After treatment the edema resolved.
Mehri Najafi Sani, Hamid Reza Kianifar, Ahmad Khodadad, Mahmoud Ahmadi, Tahereh Falsafi, Gholamreza KHATAMI,
Volume 19, Issue 3 (11-2005)

Objective: To investigate the importance of endoscopic nodular gastritis associated With Helicobacter pylori infection in children. Methods: In this prospective study, 220 consecutive patients (age range 2 to 15 years, mean age 9. 02 ±3 .3 ), 118 of them males (53. 6%) underwent upper endoscopy during evaluation of chronic abdominal pain. The appearance of nodular gastritis was observed during endoscopy by the author. Culture, rapid urease test and staining were carried out on gastric mucosal biopsies. With histological examination the presence of Helicobacter pylori and the nature of inflammation was assessed. Results: H. pylori infection was identified in 110 (50%) patients. Endoscopic nodular gastritis was seen in 100 patients ( 45.5% ), and was significantly associated with active chronic gastritis. Nodularity in the stomach showed a sensitivity of72. 7% and a specificity of81.8% and a ppv of 80% for the diagnosis of H. pylori infection and was observed in 80 (72. 7% of) H. pylori positive cases. Antral nodularity was associated with increasing risk of infection with H. pylori (OR=12, 95% CI: 6.3-22.7). Conclusion: Endoscopic findings of antral nodularity in children may suggest the presence of H. pylori infection.
F Ahmadi, M Lessan-Pezeshki, M.r KHATAMI, M Mahdavi-Mazdeh, S Maziar, S Seifi,
Volume 19, Issue 4 (2-2006)

Background: Calcineurin inhibitors (CNI) have significantly reduced the incidence of acute rejection. Nephrotoxicity however may contribute to long-term allograft dysfunction. Mycophenolate mofetil (MMF) may allow cyclosporine (CsA) dose reduction without increasing the risk of rejection. Methods: In seventy-eight living unrelated kidney transplant patients with renal dysfunction, we studied the effect of CsA dose reduction in association with MMF on renal function and cardiovascular risk profile. Results: We reduced the cyclosporine dose from mean 3.5±0.94 mg/kg/d to 2±0.51 mg/kg/d,p
Rasoul Azizi, Negin Farsi, Tahmineh Motevasseli, Seyed-Mohammad Fereshtehnejad, Abdoreza KHATAMI,
Volume 24, Issue 4 (2-2011)


 Background: Misdiagnosis of the acute appendicitis may increase the rate of negative

 appendectomies, which involve a huge waste of resources and are sometimes

 associated with severe complications. Furthermore, false negative result of ultrasonography

 (US) could lead to perforation of appendix. Since ultrasonography is still

 the most common imaging technique used in Iranian appendicitis patients, the study focused

 on evaluate the accuracy of ultrasonograghy in an educational hospital in Iran.

 Methods: We retrospectively reviewed the results of ultrasonograghy in 270 patients

 who referred to Rasoul-e-Akram hospital in Tehran, Iran, between April 2002

 and October 2004 with acute abdominal symptoms suggestive of appendicitis. The

 results of ultrasonography were compared with the histopathologic reports of biopsies

 as a gold standard. In data analysis Chi-square, independent t-test and Mann-

 Whitney U-test were performed.

 Results: The accuracy of ultrasonograghy in acute appendicitis was 60.4% and

 the rate of negative appendectomy was 17.4%. Diagnostic values of US were calculated

 as the sensitivity of 55.4% [95% confidence interval (CI)=48.6-62], specificity

 of 72.3% (95%CI=57.1-83.9), positive predictable value (PPV) of 90.4% (95%CI=

 83.9-94.6) and negative predictable value (NPV) 25.6% (95%CI=18.6-34).

 Conclusion: Although the results of our study implied that the diagnostic values

 of ultrasonography were not considerable, but it is still the only imaging techniques

 available for patients in Iran. In reference to the low NPV, using an alternative technique

 such as abdominal CT scan is recommended. More attention must be paid on

 the signs and symptoms related to acute appendicitis in such patients especially in

 teaching hospitals.

Mojtaba Sedaghat Siyahkal, Farnaz KHATAMI,
Volume 28, Issue 1 (1-2014)

  Background: There are challenges ahead of short-term hospitalization of low-risk patients hospitalized only for monitoring of severe disease who may die soon after admission. The purpose of this study was to suggest strategies for the management of ICU stay lengths and to ensure optimal use of ICU resources.

  Methods: The study was conducted retrospectively on 246 patients admitted to 9 general ICUs in Tehran, from September 2011 to March 2012. Patients staying for ≤2 days in the ICU were compared to each other after being categorized into two medical and surgical groups.

  Results: Of 129 patients with ≤2 days ICU stay (52.4%), 88.4% survived. Of these, 25 (19.4%) were placed in the medical and 104 (80.6%) to surgical groups. Survival rates were significantly greater in surgical group only 7.7% of them were in need of mechanical ventilation in the first 24 hours of admission (p<0.001). In contrast to medical group, the average Acute Physiology and Chronic Health Evaluation (APACHE) II score in the surgical group was significantly lower (9.8±3.6 and 17.3±5.8) (p<0.001).

  Conclusion: The majority of patients with ≤2 days LOS in the surgical group hospitalized for monitoring after surgery had low mortality rate and APACHE-II score. Therefore, it would seem that transferring such patients to the intermediate care unit leads to more efficient and optimal use of ICU resources.


Taraneh Yazdanparast, Kamran Yazdani, Philippe Humbert, Alireza KHATAMI, Saman Ahmad Nasrollahi, Hournaz Hassanzadeh, Amir Houshang Ehsani, Leila Izadi Firouzabadi, Alireza Firooz,
Volume 32, Issue 1 (2-2018)

    Background: Skin biometrology is a useful method for evaluation of inflammatory skin disorders such as dermatitis, psoriasis, and lichen planus. The current study tries to compare the biophysical features of skin in dermatitis, psoriasis, and lichen planus.
   Methods: By a convenient sampling method, 22 mild to moderate chronic dermatitis, 26 psoriasis, and 21 lichen planus patients were recruited in the study. Stratum corneum (S.C.) hydration, Transepidermal water loss (TEWL), pH, erythema, melanin, sebum, friction, elasticity parameters (R0, R2, and R5), skin temperature, skin thickness, and echo-density of epidermis and dermis were measured on the lesional (selected active lesion), uninvolved perilesional, and uninvolved symmetrical skin. The average of perilesional and symmetrical uninvolved parameters was used as control, while the percentage change of each parameter [(lesion – control / control) ×100] was calculated, and compared among three diseases by ANOVA test using SPSS software version 18. The significance level was set at α=0.05.
   Results: Comparison of percentage changes showed that the changes in TEWL, friction index, sebum content, R2 (gross elasticity), R5 (net elasticity), skin temperature, dermal thickness, and epidermal density are not significantly different among three skin diseases. But there were significant differences in three diseases considering the decrease in S.C. hydration (p<0.001), R0 (opposed to firmness) (p<0.001), and dermal density (p<0.001) compared to control skin. Moreover, the increase in skin pH (p<0.001), melanin content (p=0.048), erythema (p=0.023), and epidermal thickness (p <0.001) significantly differed among these diseases.
   Conclusion: Dermatitis, psoriasis and lichen planus lesions had specific biophysical changes. It may be helpful in their differential diagnosis.

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