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Showing 13 results for MORTAZAVI

Volume 8, Issue 2 (8-1994)

Non-epithelial, benign extracranial neurogenic tumors of the nasal cavities are reported in the literature with extreme rarity. These tumors differ from the more common congenital gliomas, encephaloceles, etc. in that they sometimes are detached from the brain tissues. These tumors have intracranial origins. They are congenital or acquired and may involve any of the nerves inside the nose. These tumors can grow to quite a large size and in such cases, lateral rhinotomy is often necessary for complete excision.
Seyed Hassan Arefi, Mohammad H. Bastan Hagh, Morteza Naghavi, Seyed Ebrahim Kassaian, Seyed Sina Marashie, Fariborz MORTAZAVI, Gita Gidasi,
Volume 10, Issue 2 (8-1996)

The "Tehran Blood Pressure Study" (TBPS) is an observational cross-sectional study performed on men and women aged 15 years or more during the years 1990-1991. The study has been designed and performed by the Tehran University of Medical Sciences' Cardiovascular Research Center, with the primary objective of determining the prevalence and distribution of high blood pressure in Tehrani adults. In addition, awareness levels, control rates, and the prevalence of other cardiovascular risk factors among those with high blood pressure, as well as associations between blood pressure (BP) levels and certain epidemiologic and anthropometric factors have been studied. The study population comprised 10180 male and female inhabitants of Tehran aged above 15, selected by random sampling in 50 districts of the city. The mean and the 95% confidence interval for systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 123 (122.8-123.4) and 75.4 (75.2-75.6), respectively. The prevalence of high blood pressure (SBP≥ 140 mmHg or DBP> 90 mmHg or drug consumption) was 17.6% in males, 17.9% in females, and 17.7% in generaL About 47% of the patients with high DBP readings were aware of their condition. In 20% of these, control of hypertension had been achieved by drug therapy in 11 %, drug therapy had failed to control hypertension, and 16% were not receiving treatment despite their awareness. High body mass index and a history of diabetes were more frequent in those with high BP readings than the general population. Of those with high BP readings, most had only mild elevations of BP (90≤ DBP≤99 or 140≤SBP≤159). Isolated high systolic blood pressure (SBP ≥140 mm Hg and DBP< 90 mmHg) was found in 36% of females and 30% of males aged above 64. The noticeable prevalence of high BP, the remarkable prevalence of isolated high systolic blood pressure in the elderly, the very low level of patient awareness and low control rates all necessitate the adoption of appropriate personal and community health policies.
H Foroutan, Sa MORTAZAVI,
Volume 10, Issue 4 (2-1997)

A rare case of diffuse lymphomatous polyposis of the gastrointestinal tract is reported in which the patient presented with abdominal pain, weight loss and bloody diarrhea. X-rays revealed multiple polyps involving the stomach, small intestine and colon. Biopsies confirmed the diagnosis of lymphomatous polyposis. The duration of symptoms and signs was 3 months. Diffuse lymphomatous polyposis of the gastrointestinal tract is a distinct entity, separated from diffuse gastrointestinal lymphoma or Mediterranean-type lymphoma
P Nasseri, A Ghavamzadeh, M Keyhani Elahi, Ra Sharifian, J Nateghi, K Alimoghadam, Mr MORTAZAVIzadeh, M Abasi, Mr Eshraghian,
Volume 15, Issue 2 (8-2001)

A retrospective study was done on 130 AML patients treated in Shariati and Imam Hospitals in Tehran from 1991 to 1997 to investigate the value of three post-remission methods of treatment. All patients who were in complete remission (CR) (Group I) had been treated with ARA-C (300 mg/m2/day continuous infusion for 5 days) and Daunorubicine (45 mg/m2/day for 3 days) as induction and early consolidation therapy. Forty patients were treated by additional similar chemotherapy as second consolidation and no further treatment was offered. Fifty patients (Group II) were treated by ARA-C (120 mg/m2 subcutaneously for 5 days), Etoposide (120 mg/m2 on day one), and Mitoxantrone (12 mg/m2 on day one) on each successive month as short-term miniconsolidation. Forty patients (Group III) were treated similarly to Group II until relapse for up to two years as long-term miniconsolidation. There was no difference in the three groups regarding mean age and other prognostic factors. Treatment related mortality and morbidity were also similar. Median duration of disease-free survival (DFS) was 36 (3.5-68 with 95% CI), 17 (12.5-21.5) and 19 (14.7-23.3) months respectively in these three groups. In a 14- month median observation there was no difference in DFS and overall survival (OS) among the three groups (p=0.7). We concluded that short- or long-term miniconsolidation chemotherapy compared to standard treatment does not improve DFS and OS in AML patients.
H Forootan Pishbijari, Sa MORTAZAVI Tabatabaei, M Jangodaz,
Volume 15, Issue 3 (11-2001)

Our aim was to evaluate the short and long term efficacy of botulinum toxin therapy in Iranian patients with achalasia. In a randomized, double blind trial, 20 patients with achalasia, referring to Imam Khomeini Hospital, received either 80 units of botulinum toxin (BT) or placebo (PL) from 1995 to 1998. Two weeks later, the response to treatment was assessed on the basis of changes in the symptom score (measured on a scale from o to 9). Patients who received PL initially were subsequently treated with BT. After two weeks and six months, assessment was repeated. Two weeks after treatment, clinical evaluation revealed that in the BT group all clinical symptoms were improved and the total symptom score had significantly decreased from 6.2±1.4 to 1.9±1.66 (p<0.05) and no significant changes were seen in the clinical score of the PL group. No significant differences were seen in the BT group comparing thoracic pain after the first two weeks. Two weeks after the first injection, patients who did not show clinical improvement received toxin with the same previous dose and re-evaluation was performed two weeks after the second injection and six months after the first injection. After six months mean symptom score was 3.4±1.9 (p<0.005) in the BT group and 2.4±1.51 (p<0.005) in the PL group. At this time clinical responses persisted in 12 patients (60%). In conclusion, injection of botulin urn toxin into the lower esophageal sphincter is an effective, safe and simple method of treatment for achalasia, especially in patients who cannot use other methods.
M Solelmani, H Mozdarani, Aa Pourfathollah, Y MORTAZAVI, K Alimoghaddam, A Hajifathali, Z Zonobi,
Volume 18, Issue 3 (11-2004)

Ex vivo expansion of human umbilical cord blood cells (HUCBC) is explored by several investigators to enhance the repopulating potential of HUCBC. The proliferation and expansion of human hematopoietic stem cells (HSC) in ex vivo culture was examined with the goal of generating a suitable clinical protocol for expanding HSC for patient transplantation. Using primary human mesenchymal stem cells, we established a serum-free culture system to expand human primitive progenitors and transplantable stem cells. Non-enriched cord blood CD34+ cells were cultured on a monolayer of human mesenchymal stem cells in the presence of tlu-ombopoietin (TPO), flt31flk2 ligand (FL), and/or stem cell factor (SCF), interleukin 6 (IL-6), interleukin 3 (IL-3) under serum-free conditions. After I or 2 weeks of culture, cells were examined for clonogenic progenitors and percentage of CD34+ CD38- cells. In the presence of TPO, FL, and SCF, fetal MSC cells supported more than a 35- and 20-fold expansion of CD34+ cells and colonyforming units in culture after 1 and 2 weeks of incubation, respectively. In addition, LTC-IC assay were expanded more than 7- and 16-fold after 1 and 2 weeks of culture, respectively. UCB-HSC can be expanded in culture to numbers theoretically adequate for safe, rapid engraftment of adult patients. Additional studies are needed to establish the functional activity of expanded UCB-HSC. This ex vivo expansion system should prove valuable in clinical settings in which stromal cells are available from recipients or stem cell donors.
Seyed Mansour Razavi, Ahmad Sabouri-Kashani, Hossein Ziaee-Ardakani, Aminreza Tabatabaei, Mojgan Karbakhsh, Hamidreza Sadeghipour, Seyed Abdolreza MORTAZAVI-Tabatabaei, Payman Salamati,
Volume 27, Issue 4 (Published 8 October 2013)


Background: Every year more than 2 million people depart from Iran to Saudi Arabia for Hajj ritual which can be faced with some different diseases. There are not much information about frequencies and trend of diseases in Hajj. The main objective of this study was to determine the trend of prevalent diseases during five consecutive Hajj rituals among Iranian pilgrims.


Methods: We established a specific surveillance system for all Iranian pilgrims who had participated in Hajj from 2004 to 2008. We monitored the pilgrims’ health status before departure, through their journey. The understudied diseases were 19 selected types of diseases in the Hajj. The occurrences of diseases were recorded on a researchers-made questionnaire. We used chi-square test for analysis with the alpha lower than 5% to reject the null hypothesis.


Results: During 5 consecutive periods, a total of 254,823 of Iranian pilgrims were monitored for more common diseases with this system. The most prevalent diseases were as follows: at least one type of respiratory involvement (71.26%), common cold like syndrome (47.15%), and musculoskeletal disorders (18.67%), The frequency of respiratory involvement was lower in 2006 than other years (p <0.001).There were statistically significant differences between the numbers of hospitalization and patients who were referred back to Iran with the year of Hajj (p <0.001).


Conclusion: Health managers should be informed about trend and frequency of more prevalent diseases in Hajj. Easy access to health information via such surveillance system can be possible.

Sedighe Moradi, Mohammad Reza Shafieepour, Maryam MORTAZAVI, Farhad Pishgar,
Volume 29, Issue 1 (1-2015)

  Background: Gestational diabetes mellitus (GDM) is common during pregnancy. This survey was designed based on the frequency of GDM among an urban population according to the American Diabetes Association (ADA) and the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria.

  Methods : We included all pregnant women who were admitted to a gynecology clinic from September 2012 until May 2013. The fasting blood sugar (FBS) was measured. Those having FBS≥ 126 mg/dl were excluded from the study. All women underwent a standard OGTT (oral glucose tolerance test) by ingesting 75g of glucose in the 24th to 32nd week of their pregnancy.

  Results : Two hundred ninety pregnant women with a mean±SD age of 27.72±5.091 years were included in the study. The mean±SD FBS, blood glucose one hour and two hours after ingesting 75g of glucose were 82.48±9.41, 146.86±34.22 and 114.21±27.79 mg/ dl, respectively. Based on the criteria of the ADA, 9.3% (n= 27) of the admitted patients suffered from GDM. For the IADPSG and the WHO, those numbers were 31% (n= 90) and 15.2% (n= 44), respectively.

  Conclusion : The prevalence of GDM was 1.5-times and 3 times higher when the IADPSG based data were compared to those of the WHO or the ADA.


Mashallah Aghilinejad, Negah Tavakolifard, Sayed Aliakbar MORTAZAVI, Elahe Kabir Mokamelkhah, Akbar Sotudehmanesh, Seyed Alireza MORTAZAVI,
Volume 29, Issue 1 (1-2015)

Background: Low back pain (LBP) is one of the most common problems among the workers of different industries. The role of occupational factors in causing the LBP has been indicated previously. LBP has great socio-economic costs and most of its costs are related to the chronic LBP. The aim of this study was to identify the occupational risk factors that are related to the progression of the LBP from acute to chronic phase. Methods: This cohort study has been conducted on 185 workers with acute LBP. Information related to their occupational exposure at baseline has been measured with a valid questionnaire using the self-report approach. Patients follow up was done monthly for three months after the start of the pain. Those workers whose occupational exposure had not changed during the follow up were divided into two groups of chronic LBP (n = 49) and cured (n = 136) according to the duration of the pain period (more or less than 3 months), and their job exposures were compared. Results: Among the physical and psychosocial risk factors, social support (OR= 0.466, CI= 0.231- 0.940) and job satisfaction (OR= 0.455, CI= 0.232-0.891), and lifting weights more than 15kg (OR=2.482, CI= 1.274-4.834) indicated a significant relationship with the chronicity of the LBP. After putting the variables into the regression model, only lifting>15kg remained statistically significant. Conclusion: According to the observed relationship between these occupational risk factors (social support, job satisfaction, lifting>15kg) and the chronicity of the LBP, there is hope that eliminating these factors in the workers with acute LBP will prevent its progression to the chronic phase.
Jalil Koohpayehzadeh, Amir Bahrami-Ahmadi, Hamidreza Kadkhodaei, Seyed Alireza MORTAZAVI, Ziba Amiri,
Volume 30, Issue 1 (1-2016)

Background: Identifying the predisposing factors of neck and shoulder complaints and finding solutions to avoid them could improve the occupational health condition of the nurses. In this study, we aimed at determining the role of psychological and physical occupational factors in developing neck and shoulder complaints among the participants.

  Methods: This analytic cross-sectional study was conducted on the nurses of main hospitals of Tehran. To study the prevalence of neck and shoulder pain, the Nordic questionnaire was used, and job content questionnaire was used to assess the psychological and physical occupational factors. Data were analyzed using SPSS and statistical methods. Independent sample t-test was used to compare the qualitative variables, and chi-square test was utilized for the statistical analysis of the qualitative variables.

  Results: Prevalence of neck and shoulder complaints among the nurses with high physical workload was significantly higher than in those nurses with low physical workload. Unlike physical workload, the prevalence of neck and shoulder complaints was not significantly different between the nurses with low or high psychological workload. Prevalence of neck and shoulder complaints among the female nurses was significantly higher than in the male nurses. In our study, only female nurses with high physical workload had been known as independent predictors of neck and shoulder complaints.

  Conclusion: Those nurses who had more workload, especially physical workload, had a higher prevalence of neck and shoulder complaints, and this fact could affect their work tasks.

Amir Bahrami-Ahmadi, Seyed Alireza MORTAZAVI, Roghayeh Soleimani, Mohammad Hasan Nassiri-Kashani,
Volume 30, Issue 1 (1-2016)

Background: There are some challenges about the role of work- related stress on development of musculoskeletal complaints. The present prospective study was conducted on nurses of Milad hospital in Tehran (Iran) to assess the role of work- related stress on development of neck and shoulder pain among nurses.

  Methods: From the 1,900 nurses who completed the registry forms, 1,450 nurses met the inclusion criteria. We divided the participants into exposed and unexposed groups according to their DASS-21 scores. We collected the data of neck and shoulder pain among the nurses at two points of the first and the second year after the study, using the Nordic Questionnaire. Qualitative and quantitative variables were compared between the exposed and unexposed variables with chi-square and independent sample t-test, respectively.

  Results: One year after the commencement of the study, 62 (9.1%) nurses in the exposed group and 36 (4.7%) in the unexposed group had been reported as new cases of neck and shoulder pain, respectively. The incidence of the new cases of neck and shoulder pain was significantly higher in the exposed group compared to the unexposed group (p= 0.001). Two years after the start of the study, at the second follow-up point, 135 (19.8%) nurses in the exposed group and 76 (9.9%) in the unexposed group had been reported as new cases of neck and shoulder pain, respectively. The incidence of new cases of neck and shoulder pain was significantly higher in the exposed group compared to the unexposed group (p<0.001).

  Conclusions: The incidence of neck and shoulder pain was higher in those nurses with high level of work- related stress. According to our results, more attention should be paid to mental health as well as physical symptoms and limitations of the healthcare workers when they refer to occupational health services with musculoskeletal pain complaints.

Hadi Ghaffari, Ahmad Tavakoli, Davod Javanmard, Hamidreza Mollaei, Helya Sadat MORTAZAVI, Seyed Hamidreza Monavari,
Volume 31, Issue 1 (1-2017)

Seyed Jalal Kiani, Davod Javanmard, Hadi Ghaffari, Ahmad Tavakoli, Helya Sadat MORTAZAVI, Farah Bokharaei-Salim, Zahra Bangaleh, Seyed Hamidreza Monavari,
Volume 32, Issue 1 (2-2018)

    Background: Different outcomes of parvovirus B19 (B19V) infection in immunocompromised patients, including HIV1-infected persons, may be life-threatening. Considering the hematologic disorders associated with B19V infection, this study aimed to investigate the prevalence of B19V infection among HIV1-infected individuals in Iran.
   Methods: Serum samples from 100 HIV1-infected patients were analyzed for B19 viral DNA using real-time PCR assay. COBAS TaqMan HIV-1 test was performed for quantitative measurements of HIV-1 RNA in the patients’ sera.
   Results: Real-time PCR analysis revealed that 10 out of 100 cases (10%) were positive for B19V infection. Across various age groups, the B19V infection was more prevalent among patients within the age range of 21-40 years. Higher prevalence of B19V infection was observed among HIV1-infected patients with a viral load of higher than 400 copies/mL.
   Conclusion: Despite limitations, this study may set the stage for further evaluations with larger sample sizes to elucidate the potential role of B19V in hematologic disorders, which may result in exacerbation of the disease in HIV1-infected patients. Moreover, as it has been shown that B19V infection can be treated using intravenous immunoglobulin (IVIG) therapy, available treatments may help improve the quality of life in HIV-infected persons.

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